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. 2016 May 5;6:25492. doi: 10.1038/srep25492

Table 7. Analyzed pathways of the potential target of Bufei Yishen formula.

Term Count % PValue
Neuroactive ligand-receptor interaction 30 0.7413 0.0000
Amyotrophic lateral sclerosis (ALS) 12 0.2965 0.0000
Pathways in cancer 27 0.6672 0.0000
Drug metabolism 12 0.2965 0.0000
Calcium signaling pathway 19 0.4695 0.0000
Bladder cancer 10 0.2471 0.0000
Metabolism of xenobiotics by cytochrome P450 11 0.2718 0.0000
Non-small cell lung cancer 10 0.2471 0.0000
Glutathione metabolism 9 0.2224 0.0001
Colorectal cancer 11 0.2718 0.0001
Small cell lung cancer 11 0.2718 0.0001
Pancreatic cancer 10 0.2471 0.0001
Prostate cancer 11 0.2718 0.0001
VEGF signaling pathway 10 0.2471 0.0002
Gap junction 10 0.2471 0.0007
Thyroid cancer 6 0.1483 0.0010
Focal adhesion 15 0.3706 0.0011
GnRH signaling pathway 10 0.2471 0.0013
Glioma 8 0.1977 0.0015
Alzheimer’s disease 13 0.3212 0.0015
Progesterone-mediated oocyte maturation 9 0.2224 0.0022
Prion diseases 6 0.1483 0.0024
T cell receptor signaling pathway 10 0.2471 0.0026
Arginine and proline metabolism 7 0.1730 0.0030
Melanoma 8 0.1977 0.0030
Fc epsilon RI signaling pathway 8 0.1977 0.0051
Toll-like receptor signaling pathway 9 0.2224 0.0061
Neurotrophin signaling pathway 10 0.2471 0.0065
NOD-like receptor signaling pathway 7 0.1730 0.0065
Apoptosis 8 0.1977 0.0093
Adipocytokine signaling pathway 7 0.1730 0.0095
Vascular smooth muscle contraction 9 0.2224 0.0111
Insulin signaling pathway 10 0.2471 0.0111
Renal cell carcinoma 7 0.1730 0.0117
Endometrial cancer 6 0.1483 0.0132
MAPK signaling pathway 15 0.3706 0.0137
Caffeine metabolism 3 0.0741 0.0142
B cell receptor signaling pathway 7 0.1730 0.0161
Arachidonic acid metabolism 6 0.1483 0.0178
Graft-versus-host disease 5 0.1235 0.0210
Phenylalanine metabolism 4 0.0988 0.0210
Tryptophan metabolism 5 0.1235 0.0228
Oocyte meiosis 8 0.1977 0.0302
ErbB signaling pathway 7 0.1730 0.0310
Tyrosine metabolism 5 0.1235 0.0312
p53 signaling pathway 6 0.1483 0.0374
Epithelial cell signaling in Helicobacter pylori infection 6 0.1483 0.0374
Type II diabetes mellitus 5 0.1235 0.0385
Complement and coagulation cascades 6 0.1483 0.0395