TABLE 1.

The z-DOPE score(Eramian et al.) (as calculated by the Sali Lab ModEVAL server: http://modbase.compbio.ucsf.edu/modeval/) and Total PRIME energy(Banks et al.; Maestro) for the homology models used in this study (Fig. 4). All numbers rounded-off to one digit after decimal.

A3 Domain	z-DOPE score	Total PRIME Energy (kCal/M)
A3B-NTD	−2	−7.8 ×103
A3B-CTD	−0.7	−8.1 ×103
A3D-NTD	−2.1	−9.3 ×103
A3D-CTD	−2.2	−8.0 ×103
A3F-NTD	−2	−7.9 ×103
A3G-NTD	−2.3	−8.1 ×103
A3H	−1.3	−7.6 ×103