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Theoretical isoelectric point (pI) values for the human APOBEC3 domains, based on the primary amino acid sequence. (Calculated using the Compute pI/MW tool located at http://web.expasy.org/compute_pi/). Domains known to bind HIV-1 Vif (Fig. 1) are indicated by an asterisk (*). All numbers rounded-off to one digit after decimal.
| Protein | NTD (pI) | CTD (pI) | Full Length (pI) |
|---|---|---|---|
| A3A | 6.3 | ||
| A3B | 5.1 | 8.1 | 5.9 |
| A3C | * 7.5 | ||
| A3D | 7.2 | * 9.3 | 8.7 |
| A3F | 5.5 | * 8.9 | 6.9 |
| A3G | * 5.9 | 9.4 | 8.3 |
| A3H | * 9.2 |
