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. 2016 May 4;11:22. doi: 10.1186/s13062-016-0124-7

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© Mercker et al. 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Section of a simulation considering an evolving tissue loop after 15 m i n, using the example of the compression-mediated feedback. a Finite element discretization, b biological cells, c mechanical cue (here tissue compression quantified by det(F)), d morphogen concentration ϕ