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. 2016 May 3;7:11415. doi: 10.1038/ncomms11415

Figure 4. Laminin inhibits the proliferation of PDGFRβ+ cells.

Figure 4

(a) Edu (green) incorporation and PDGFRβ (red) expression in hindlimb muscles from 2-month-old mice. (b,c) Quantification of total Edu+ cells (b) and Edu+PDGFRβ+ and Edu+ALP+ cells (c) in a; n=4. (d) Edu (red) incorporation in freshly isolated pericytes in the presence of saline or exogenous laminin. Ln, laminin; Sal, saline. (e) Quantification of Edu+ cells in d; n=6. (f) Edu (green) and PDGFRβ (red) expression 4 days after CTX injection in wild-type mice in the presence of saline or laminin. (g–i) Quantification of PDGFRβ expression (g), total Edu+ (h) and Edu+PDGFRβ+ cells (i) in tibialis anterior muscles; n=3. Scale bars, 25 μm in a, 100 μm in d and 50 μm in f. *P<0.05; **P<0.01; ***P<0.001; ###P<0.001 (Student's t-test). The results are shown as mean±s.d.