Table 1.
Bio-signals and autonomic parameters at rest in 25 post-mTBI-patients and 29 healthy controls
| Parameters at rest | Healthy controls | Post-mTBI-patients | Controls vs. patients |
|---|---|---|---|
| RRI [ms] | 908.4 ± 132.9 | 868.7 ± 138.0 | P = 0.17 |
| BPsys [mmHg] | 130.6 ± 17.0 | 127.5 ± 16.6 | P = 0.51 |
| BPdia [mmHg] | 66.6 ± 8.6 | 66.1 ± 7.6 | P = 0.82 |
| Respiration [min-1] | 13.1 ± 3.8 | 14.8 ± 3.6 | P = 0.101 |
| RRI-SD [ms] | 59.0 ± 29.3 | 38.6 ± 18.6 | P = 0.005 |
| RRI-CV [ms] | 6.6 ± 3.3 | 4.5 ± 2.1 | P = 0.02 |
| RRI-RMSSD [ms] | 48.4 ± 27.8 | 31.2 ± 18.3 | P = 0.02 |
| BRS [ms/mmHg] | 12.4 ± 5.9 | 9.2 ± 4.0 | P = 0.043 |
| RRI-LF-powers [ms2] | 2417.7 ± 2441.6 | 953.5 ± 867.8 | P = 0.009 |
| RRI-HF-powers [ms2] | 1188.7 ± 1374.6 | 567.4 ± 581.9 | P = 0.032 |
| RRI-total-powers [ms2] | 3606.4 ± 3544.7 | 1520.9 ± 1300.25 | P = 0.009 |
| RRI-LF/HF-ratio | 3.0 ± 2.1 | 3.6 ± 3.1 | P = 0.42 |
| BPsys-LF-powers [mmHg2] | 12.5 ± 3.9 | 9.7 ± 4.0 | P = 0.014 |
| BPsys-HF-powers [mmHg2] | 5.1 ± 2.2 | 4.6 ± 3.0 | P = 0.25 |
Mean values ± standard deviation of RR-intervals, systolic and diastolic blood pressures, respiratory frequency, time domain parameters of RRI-variability, and frequency domain parameters reflecting powers of autonomic modulation of RR-intervals and systolic blood pressures in 25 patients with a history of mild TBI and 29 healthy controls at rest. Significant differences (p < 0.05) between patients with a history of mTBI (post-mTBI-patients) and healthy participants are indicated in italic and bold
mTBI mild traumatic brain injury, RRI RR-interval, BPsys systolic blood pressure, BPdia diastolic blood pressure, SD standard deviation, CV coefficient of variation, RMSSD root mean square of the successive differences, BRS baroreflex sensitivity, LF low frequency, HF high frequency