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PG inhibits cell proliferation and induces apoptosis in KB cells. KB cells were incubated with PG at the indicated concentration for 48 h when no time is indicated. (A) PG inhibits cell proliferation in KB cells in a dose- and time-dependent manner. (B) PG induces apoptosis in a dose-dependent manner. (C) PG activates caspase-3 in a dose-dependent manner. (D) Z-VAD-FMK significantly blocks PG-induced apoptosis in KB cells. Mean±SD. n=3. *P<0.05, **P<0.01.
