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PG induces apoptosis in KB cells by targeting survivin. KB cells were challenged with PG at the indicated concentration (50 μg/ml if not indicated) for 48 h. (A) PG suppresses the mRNA expression of survivin in a concentration-dependent manner. (B) PG concentration-dependently suppresses survivin protein expression. (C) Flow cytometric analysis showing the apoptosis-inducing effect of PG in survivin overexpressing KB cells. Mean±SD. n=3. *P<0.05, **P<0.01.
