Figure 10.

Protein expression levels of anti-fibrotic, anti-inflammatory, antioxidant and endothelial function biomarkers in lung parenchyma at day 60 after the TAC procedure. (A) Protein expression of p-Smad1/5. (B) Protein expression of bone morphogenetic protein (BMP)-2. (C) Protein expression of Bcl-2. (D) Protein expression of endothelial nitric oxide synthase (eNOS). (E) Protein expression of heme oxygenase (HO)-1. (F) Protein expression of NAD(P)H quinone oxidoreductase (NQO) 1. (G) Protein expression of glutathione reductase (GR). (H) Protein expression of glutathione peroxidase (GPx). All statistical analyses were performed by one-way ANOVA followed by Bonferroni multiple comparison post hoc test. SC=Sham control. TAC=Transverse aortic constriction. Mean±SEM. n=8 for each group. ^**P<0.01 vs SC group. ^##P<0.01 vs TAC group.