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. 2016 Apr 11;37(5):589–603. doi: 10.1038/aps.2015.162

Figure 9.

Figure 9

Protein expression levels of inflammatory, apoptotic and fibrotic markers in lung parenchyma at day 60 after the TAC procedure. (A) Protein expression of tumor necrosis factor (TNF)-α. (B) Protein expression of nuclear factor (NF)-κB. (C) Protein expression of matrix metalloproteinase (MMP)-9. (D) Protein expression of mitochondrial Bax (mit-Bax). (E) Protein expression of cleaved caspase (c-Casp) 3. (F) Protein expression of cleaved poly (ADP-ribose) polymerase (c-PARP). (G) Protein expression of phosphorylated (p)-Smad3. (H) Protein expression of transforming growth factor (TGF)-β. All statistical analyses were performed by one-way ANOVA followed by Bonferroni multiple comparison post hoc test. SC=sham control. TAC=Transverse aortic constriction. Mean±SEM. n=8 for each group. **P<0.01 vs SC group. ##P<0.01 vs TAC group.