Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) Structure of the O-fucose glycan found on mammalian Notch.
(B) The O-fucose glycan of Notch causes a decrease in Jagged1-mediated stimulation. By eliminating specific monosaccharides on the Notch glycan using genetic methods, it was found that a trisaccharide was the minimum structure necessary to decrease Jagged1 activity.
