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(A) NeuAc-containing glycans and HS GAGs were chemically appended to a ketone-functionalized polymer and inserted into the plasma membrane using a phospholipid tail.
(B) CS GAGs were displayed on the cell surface by functionalization onto ketone-containing liposomes.
(C) Genetic incorporation of the HaloTag protein allowed for the immobilization of HS GAGs modified with a chlorohexyl linker.
