TABLE 2.
Univariate and multivariable analyses of primary and secondary outcomes in those with preoperative thrombocytopenia compared to those with PLT counts of more than 100 × 109/L
Outcome | Univariate analysis
|
Multivariable analysis†
|
||||
---|---|---|---|---|---|---|
OR* | 95% CI | p value | OR* | 95% CI | p value | |
Perioperative RBCs | 4.48 | 3.89–5.15 | <0.0001 | 2.15 | 1.72–2.68 | <0.0001 |
Intraoperative RBCs | 3.96 | 3.42–4.58 | <0.0001 | 1.67 | 1.31–2.12 | <0.0001 |
Reoperation | 4.12 | 3.14–5.40 | <0.0001 | 1.75 | 1.18–2.59 | 0.0053 |
Mortality | 6.39 | 5.04–8.10 | <0.0001 | 1.87 | 1.29–2.70 | 0.0009 |
ORs are for preoperative thrombocytopenia. ORs higher than 1.00 indicate increased likelihood of the listed outcome in patients with thrombocytopenia.
Adjusted including all baseline characteristics having significant differences between patient groups with PLT counts of more than 100 × 109/L and those with PLT counts of not more than 100 × 109/L, utilizing a threshold p value of less than 0.1. Variables included in conditional logistic regression modeling—age; sex; Charlson score; perioperative warfarin, heparin; preoperative Hb, PLT count, INR, creatinine; ASA type (“ASA 1” as reference); emergency surgery; procedure type (“general surgery” as reference); anesthetic type (general vs. regional); surgical duration.