TABLE 3.

Univariate analyses of primary and secondary outcomes by the presence or absence of preoperative PLT transfusion in patients with thrombocytopenia

Outcome*	No therapy (n =789)	Preoperative PLTs (n =71)	p value†	Estimate (95% CI)‡
Perioperative RBC transfusion	387 (49)	47 (66)	0.0065	2.03 (1.22–3.39)
Intraoperative RBC transfusion	301 (38)	32 (45)	0.2527	1.33 (0.82–2.17)
Reoperation	63 (8)	7 (10)	0.5806	1.23 (0.55–2.87)
ICU admission	232 (30)	41 (58)	<0.0001	3.26 (1.99–5.36)
ICU length of stay (days), n =273§	1.8 (0.8, 3.8)	2.6 (1.2, 3.9)	0.2659	0.12 (−0.73 to 0.86)
Postoperative MV	56 (8)	8 (14)	0.1006	1.95 (0.88–4.31)
Duration of MV (days), n =64§	1.1 (0.1, 5.1)	6.5 (2.0, 17.2)	0.0618	5.8 (−1.8 to 13.3)
Hospital LOS (days), n =859§	8.7 (3.5, 17.3)	15.1 (6.5, 41.1)	<0.0001	9.3 (3.1–15.9)
Mortality	80 (10)	19 (27)	<0.0001	3.20 (1.80–5.67)

^*Data are reported as number (%) for binary outcomes and median (Q1, Q3) for continuous outcomes.

^†p values are from logistic regression for binary outcomes and the rank-sum test for continuous outcomes.

^‡For binary outcomes the estimate is for the OR for preoperative PLT transfusion versus no therapy. For continuous outcomes the estimate is the difference in mean (preoperative PLTs minus no therapy) with the 95% CI calculated from 1000 bootstrap samples.

^§ICU length of stay is summarized only for those patients who were admitted to the ICU and duration of mechanical ventilation is summarized only for those patients who received mechanical ventilation postoperatively.

MV =mechanical ventilation; LOS =length of stay.