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. Author manuscript; available in PMC: 2016 May 5.
Published in final edited form as: Anesthesiology. 2015 Jan;122(1):21–28. doi: 10.1097/ALN.0000000000000513

Table 4.

Product-specific Incidence Rates of Perioperative Transfusion-associated Circulatory Overload Overall and by Index Year

Overall No./Total (%) 2004 No./Total (%) 2011 No./Total (%)
Erythrocytes only 90/3,322 (2.7) 74/1,853 (4.0) 16/1,469 (1.1)
FFP only 11/93 (11.8) 7/34 (20.6) 4/59 (6.8)
Platelets only 2/89 (2.2) 0/32 (0.0) 2/57 (3.5)
Mixed products 73/564 (12.9) 38/243 (15.6) 35/321 (10.9)

Multivariable logistic regression analyses demonstrated that the frequency of transfusion-associated circulatory overload was related to both blood product group (P < 0.001) and calendar year (P < 0.001). Two patients were excluded from this secondary analysis (one received only fresh whole blood and one received only cryoprecipitate; neither experienced transfusion-associated circulatory overload).

FFP = fresh-frozen plasma.