Skip to main content
. 2016 May 5;6:25457. doi: 10.1038/srep25457

Figure 5. Identification of receptor-expressing cells in the hippocampus following systemic LPS challenge.

Figure 5

Double immunofluorescence study revealed that CCR2-expressing cells in the hippocampal parenchyma were immunopositive for GFAP, indicative of astrocytes (a–c). CCR2 expression was especially pronounced in astrocytic endfeet surrounding blood vessels. CXCR2-expressing cells in the hippocampal parenchyma were immunopositive for GFAP, indicative of astrocytes (d–f). CXCR2 expression was especially pronounced just underneath the pia (d–f). IL-6R-expressing cells in the hippocampal parenchyma were immunopositive for GFAP, indicative of astrocytes (g–i). Nuclei were counterstained with DAPI. All photoimages were obtained from LPS-treated mice. Scale bars 50 μm.