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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2015 Jun 4;11(1):36–47. doi: 10.1007/s11481-015-9617-x

Fig. 3.

Fig. 3

Impact of Apigenin on antigen uptake and immune cell adhesion. Splenocytes from both the EAE + Vehicle and EAE + Apigenin groups of C57BL/6 (n=2/group) and SJL/J mice (n=5/group) were stimulated with MOG38–49 and PLP323–339 peptides respectively for 3 days followed by activation with PMA, ionomycin and brefeldin A for 5 h. These cells were subsequently stained with antibodies against CD11c, CD8α, α4, and CLEC12A. Data represents dendritic cells from C57BL/6 (a) and SJL/J (b) mice expressing α4 integrin (top) and CLEC12A (bottom) upon stimulation with MOG38–49 and PLP323–339 respectively. Each bar is representative of the mean percentage for every marker per group. Histogram plots are representative of one animal per group. *p<0.05