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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Neuroimmune Pharmacol. 2015 Jun 4;11(1):36–47. doi: 10.1007/s11481-015-9617-x

Fig. 4.

Fig. 4

Effect of Apigenin on Treg and Th17 balance in neuroinflammation. Flow cytometry analysis representing CD4+ cells from C57BL/6 mice (a) and SJL/J mice (b) expressing IL-17A (top) and CD25+FOXP3 (bottom) upon stimulation with MOG38–49 and PLP323–339 peptides respectively for 3 days followed by activation with PMA, ionomycin and brefeldin A for 5 h. Each bar is representative of the mean percentage for every marker per group. Contour plots representative of one animal per group are shown on the left. *p<0.05