Figure 1.

Change in plasma creatinine concentration before and after establishment of euthyroidism in 19 cats with iatrogenic hypothyroidism. Dotted line represents the upper limit of the laboratory¹ reference interval for plasma creatinine concentration (2 mg/dL). Change in plasma creatinine concentration between the hypothyroid and euthyroid visits was assessed by Wilcoxon signed rank test with statistical significance defined as P < .05. Plasma creatinine concentration decreased significantly after restoration of euthyroidism (P < .001).