Table 1.
Selected clinicopathologic variables before and after establishment of euthyroidism in 19 cats with iatrogenic hypothyroidism. N/A, not applicable. Wilcoxon signed rank test was used to compare variables between the hypothyroid and euthyroid visits. Variables highlighted in bold were significantly different between the 2 visits (P < .05)
| Variable | Laboratory1 Reference Interval | Hypothyroid Visit | Euthyroid Visit | P‐Value |
|---|---|---|---|---|
| Median [25th, 75th Percentile] | Median [25th, 75th Percentile] | |||
| Plasma urea concentration (mg/dL) | 15.1–59.6 | 42.3 [37.2, 57.1] | 43.4 [31.4, 64.7] | .19 |
| Plasma creatinine concentration (mg/dL) | 0.22–2.00 | 2.61 [1.90, 3.26] | 2.07 [1.42, 2.82] | <.001 |
| Plasma alanine aminotransferase activity (IU/L) | 5.0–60.0 | 74.7 [42.7, 85.6] | 69.6 [52.1, 135.8] | .077 |
| Plasma alkaline phosphatase activity (IU/L) | <60.0 | 26.6 [17.0, 33.0] | 38.0 [23.5, 46.5] | <.001 |
| Plasma cholesterol concentration (mg/dL) | 85.1–154.7 | 189.2 [166.0, 281.9] | 200.8 [146.7, 247.1] | .47 |
| Plasma total calcium concentration (mg/dL) | 8.2–11.8 | 10.6 [10.0, 11.6] | 10.4 [9.9, 11.1] | .14 |
| Packed cell volume (%) | 26–45 | 30 [28, 39] | 34 [29, 39] | .038 |
| Body weight (kg) | N/A | 4.03 [3.59, 4.53] | 3.89 [3.34, 4.18] | .019 |
| Body condition score (/9) | N/A | 4 [3, 5] | 5 [3, 6] | .37 |
| Mean systolic blood pressure (mmHg) | N/A | 130.6 [122.0, 140.7] | 135.4 [129.8, 140.7] | .81 |
| Heart rate (bpm) | N/A | 174 [163, 201] | 190 [164, 212] | .009 |