Table 6.
Factors associated with disease‐free interval (DFI), survival times, or both (ST) in univariable analysis for the modified intent‐to‐treat analysis.
| Variable | DFI | ST | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age at diagnosis (years) | 0.99 (0.95, 1.04) | .69 | 1.05 (1.01, 1.09) | .02 |
| Body weight (kg) | 1.02 (1.01, 1.03) | <.001 | 1.02 (1.01, 1.03) | <.001 |
| Pure breed dog | 1.40 (1.04, 1.87) | .027 | 1.35 (1.06, 1.72) | .016 |
| Proximal humeral tumor | 1.50 (1.16, 1.93) | .0017 | 1.49 (1.20, 1.85) | <.001 |
| ALP (continuous) | 1.001 (1.000, 1.001) | .0084 | 1.000 (1.000, 1.001) | .048 |
| Lymphocyte count (continuous) | 0.82 (0.66, 1.02) | .074 | 0.78 (0.65, 0.93) | .006 |
| Treatment delays (continuous) | 0.85 (0.76, 0.96) | .007 | 0.92 (0.83, 1.00) | .06 |
| Summation dose intensity | 2.82 (1.05, 7.63) | .04 | 1.84 (0.82, 4.14) | .14 |
| Treatment following development of metastatic disease | – | – | 1.89 (1.41, 2.54) | <.0001 |
HR, hazard ratio.