In dogs with advanced myxomatous mitral valve disease, 9 variables representing the parasympathetic modulation of heart rate (HR) (including (A)
HFn24) were significantly lower in dogs with a history of syncope compared with dogs without a history of syncope. However, 1 variable, (B)
LFn24, suggested to represent both the parasympathetic and sympathetic modulation of HR, was significantly higher in dogs with a history of syncope. HFn24, high frequency measured over a 24‐hour period; LFn24, normalized low frequency measured over a 24‐hour period.