Table 3. Prescription drug categories used in xerostomia and non-xerostomia patients.
| Prescription drug categories1 | Xerostomia2 (n = 72) | Non-xerostomia (n = 246) | XerostomiaOR (95% CI) | P-value3 |
|---|---|---|---|---|
| Number of patients (%) | Number of patients (%) | |||
| Antihistamines | 22 (31) | 27 (11) | 2.8 (1.4–5.6) | 0.004 |
| Diuretics | 7 (10) | 5 (2) | 4.0 (1.1–14.2) | 0.033 |
| Antidepressants | 12 (17) | 13 (5) | 2.1 (0.8–5.2) | 0.109 |
| Anxiolytics | 12 (17) | 26 (11) | 0.8 (0.3–1.7) | 0.492 |
| Medications against urge incontinence | 3 (4) | 3 (1) | 1.7 (0.3–9.6) | 0.529 |
| Oral contraceptives | 1 (2) | 9 (8) | 0.5 (0.1–4.6) | 0.5504 |
| Antihypertensives | 8 (11) | 11 (5) | 1.3 (0.5–3.8) | 0.615 |
| Antitussives | 8 (11) | 20 (8) | 1.3 (0.5–3.2) | 0.625 |
| Medications against dyspepsia and gastro-esophageal reflux | 5 (7) | 10 (4) | 1.2 (0.4–4.1) | 0.771 |
| Anti-Parkinsonian medications | 1 (1) | 1 (0) | 1.2 (0.1–20.4) | 0.903 |
| Hormone replacement therapy | 7 (12) | 9 (8) | 1.1 (0.4–3.2) | 0.9084 |
| Medications against chronic obstructive pulmonary disease | 1 (1) | 1 (0) | 0.9 (0.1–14.8) | 0.922 |
| Medications against benign prostatic hyperplasia | 0 (0) | 4 (3) | 0 (0) | 0.9995 |
| Medications against acne | 0 (0) | 1 (0) | 0 (0) | 1.0 |
| Antipsychotics | 0 (0) | 0 (0) | - | - |
OR = odds ratio; CI = confidence interval
1As defined by the McMonnies Dry Eye Questionnaire.
2Daily dry mouth for the last three months
3Logistic regression analysis adjusted for age and sex, unless otherwise stated.
4Analysed in female patients (n = 166) and adjusted for age.
5Analysed in male patients (n = 152) and adjusted for age.