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. 2016 May 5;11(5):e0154843. doi: 10.1371/journal.pone.0154843

Table 2. Univariate Cox proportional hazards model for IPT abandonment-free survival of children and adolescents with LTBI in the state of Rio de Janeiro, 2002–2009.

VARIABLE HR (95%) CI P
Gender (n = 245)
Female/Male 0.771 0.46–1.27 0.30
Age range (n = 245)
Children (< 10 years old)/ Adolescents (10 years old) 1.381 0.70–2.73 0.34
Contact with pulmonary TB (n = 245)
Yes/No 2.521 0.62–10.3 0.20
Contact with index case that was not undergoing anti-TB treatment (n = 202)
Yes/No 7.871 1.08–57.3 0.04
Body weight (percentile) (n = 245)
10/<10 1.321 0.41–4.22 0.64
Tuberculin skin test (mm) (n = 236)
10/<10 1.401 0.69–2.34 0.31
IPT adverse effects (n = 245)
Yes/No 1.831 0.57–5.84 0.30
HIV serum status (n = 68)
Positive/Negative 0.331 0.76–1.41 0.14
Place of residence (n = 286)
City of Rio de Janeiro/Out of the City of Rio de Janeiro 1.421 0.70–2.89 0.32
Place of residence’s HDI (n = 245) 0.04 0.00–0.42 0.02
Driving distance between place of residence and HMJ (km) (n = 245) 1.02 0.99–1.04 0.06
Number of different transport means from the place of residence to HMJ (n = 245)
2/<2 1.291 0.91–1.83 0.14

CI—confidence interval

HDI—human development index

HIV—human immunodeficiency virus

HMJ—Jesus Municipal Hospital

HR—hazard ratio

TB—tuberculosis

IPT—isoniazid preventive therapy