Table 2. Univariate Cox proportional hazards model for IPT abandonment-free survival of children and adolescents with LTBI in the state of Rio de Janeiro, 2002–2009.
VARIABLE | HR | (95%) CI | P |
---|---|---|---|
Gender (n = 245) | |||
Female/Male | 0.771 | 0.46–1.27 | 0.30 |
Age range (n = 245) | |||
Children (< 10 years old)/ Adolescents (≥10 years old) | 1.381 | 0.70–2.73 | 0.34 |
Contact with pulmonary TB (n = 245) | |||
Yes/No | 2.521 | 0.62–10.3 | 0.20 |
Contact with index case that was not undergoing anti-TB treatment (n = 202) | |||
Yes/No | 7.871 | 1.08–57.3 | 0.04 |
Body weight (percentile) (n = 245) | |||
≥10/<10 | 1.321 | 0.41–4.22 | 0.64 |
Tuberculin skin test (mm) (n = 236) | |||
≥10/<10 | 1.401 | 0.69–2.34 | 0.31 |
IPT adverse effects (n = 245) | |||
Yes/No | 1.831 | 0.57–5.84 | 0.30 |
HIV serum status (n = 68) | |||
Positive/Negative | 0.331 | 0.76–1.41 | 0.14 |
Place of residence (n = 286) | |||
City of Rio de Janeiro/Out of the City of Rio de Janeiro | 1.421 | 0.70–2.89 | 0.32 |
Place of residence’s HDI (n = 245) | 0.04 | 0.00–0.42 | 0.02 |
Driving distance between place of residence and HMJ (km) (n = 245) | 1.02 | 0.99–1.04 | 0.06 |
Number of different transport means from the place of residence to HMJ (n = 245) | |||
≥2/<2 | 1.291 | 0.91–1.83 | 0.14 |
CI—confidence interval
HDI—human development index
HIV—human immunodeficiency virus
HMJ—Jesus Municipal Hospital
HR—hazard ratio
TB—tuberculosis
IPT—isoniazid preventive therapy