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. 2016 May 5;11(5):e0154077. doi: 10.1371/journal.pone.0154077

Fig 1. Spontaneous left atrial (LA) ectopy is dependent on intrinsic triggered activity generated in the left atrial posterior wall (LAPW).

Fig 1

(a) Light field image of the murine LA showing the anatomical position of the left atrial appendage (LAA) and the LAPW. (b) Example intracellular recordings taken from the same LA with the LAPW attached (intact LA) and after the LAPW has been removed (resected). Ectopic action potentials are abolished following LAPW resection. (c) Number of LA that developed spontaneous ectopic activity before and after LAPW resection. ***denotes P<0.001, Fisher’s exact test, N = 19 LA. (d) Example traces demonstrating different types of ectopic activity. (e) Direct recordings made from the LAA (upper) and LAPW (lower) following LAPW resection. Only the LAPW displays intrinsic ectopic activity. (f) Number of isolated LAA and LAPW preparations that display intrinsic ectopic activity.