Fig 6. I_to reduction in cardiomyocytes isolated from the left atrial poisterior wall (LAPW).

(a) Example voltage-sensitive, Ca²⁺ independent, macroscopic K⁺ currents evoked in cardiomyocytes isolated from the left atrial appendage (LAA, left) and LAPW (right). Voltage protocol is shown inset. (b-d) LAA and LAPW I/V relationships for the peak outward K⁺ current, I_to and steady state K⁺ current. Data presented as mean ± SEM. * denotes P<0.05 LAA (N = 16 cells) v LAPW (N = 12 cells), two way repeated measures Analysis of Variance (ANOVA) with Bonferroni post hoc analysis.