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. Author manuscript; available in PMC: 2016 May 5.
Published in final edited form as: JAMA. 2015 Nov 3;314(17):1850–1860. doi: 10.1001/jama.2015.13134

Figure 3. African Elephant and Human Peripheral Blood Lymphocytes and Sensitivity to Ionizing Radiation.

Figure 3

A, The percentage of late apoptosis (annexin V positive [AV+] and propidium iodide positive [PI+]) and B, early apoptosis (AV+PI−) in elephant peripheral blood lymphocytes compared with human peripheral blood lymphocytes in response to 2 Gy and 6 Gy of ionizing radiation are graphed. Significant differences computed with a 2-sided t test between human and elephant at 0, 5, 10, 18, and 24 hours are indicated. Error bars represent 95% CIs. C, Representative scatter plots from flow cytometry are shown from the 0- and 18-hour time points. NT indicates no treatment.

aP <. 001.

bPanel A: NT at 10 hours, P = .008. Panel B: NT at 0 hours, P = .002; 2 Gy at 5 hours, P = .003; 6 Gy at 5 hours, P = .004.

cP = .03.