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. Author manuscript; available in PMC: 2016 May 5.
Published in final edited form as: JAMA. 2015 Nov 3;314(17):1850–1860. doi: 10.1001/jama.2015.13134

Table 2.

pH2AX Foci in Human and African Elephant Cells After 2 Gy of Ionizing Radiationa

Treatment and Time Frame Viable Cells With Indicated No. of pH2AX Foci, %

0–5 Foci 6–10 Foci 11–15 Foci 16–≥20 Foci




Human Elephant Human Elephant Human Elephant Human Elephant
No treatment, 1 h 97.3 98.7 2.7 1.3 0.0 0.0 0.0 0.0

No treatment, 5 h 97.7 98.0 2.3 1.3 0.0 0.7 0.0 0.0

No treatment, 24 h 99.7 99.7 0.3 0.3 0.0 0.0 0.0 0.0

2 Gy, 1 h 23.0 26.3 25.3 33.7 19.0 17.0 32.7 23.0

2 Gy, 5 h 46.7 51.0 32.7 39.0 14.3 9.0 6.3 1.0

2 Gy, 24 h 94.3 92.3 5.3 7.3 0.3 0.0 0.0 0.0
a

Foci indicate remaining DNA double-stranded breaks. Cells are binned by the number of phospho-histone H2AX (pH2AX) foci and demonstrate no significant difference in the rate of DNA damage repair between human and elephant (P > .05 by χ2 test).