Table 2.
Treatment and Time Frame | Viable Cells With Indicated No. of pH2AX Foci, % | |||||||
---|---|---|---|---|---|---|---|---|
0–5 Foci | 6–10 Foci | 11–15 Foci | 16–≥20 Foci | |||||
Human | Elephant | Human | Elephant | Human | Elephant | Human | Elephant | |
No treatment, 1 h | 97.3 | 98.7 | 2.7 | 1.3 | 0.0 | 0.0 | 0.0 | 0.0 |
No treatment, 5 h | 97.7 | 98.0 | 2.3 | 1.3 | 0.0 | 0.7 | 0.0 | 0.0 |
No treatment, 24 h | 99.7 | 99.7 | 0.3 | 0.3 | 0.0 | 0.0 | 0.0 | 0.0 |
2 Gy, 1 h | 23.0 | 26.3 | 25.3 | 33.7 | 19.0 | 17.0 | 32.7 | 23.0 |
2 Gy, 5 h | 46.7 | 51.0 | 32.7 | 39.0 | 14.3 | 9.0 | 6.3 | 1.0 |
2 Gy, 24 h | 94.3 | 92.3 | 5.3 | 7.3 | 0.3 | 0.0 | 0.0 | 0.0 |
Foci indicate remaining DNA double-stranded breaks. Cells are binned by the number of phospho-histone H2AX (pH2AX) foci and demonstrate no significant difference in the rate of DNA damage repair between human and elephant (P > .05 by χ2 test).