. 2015 Oct 23;124(5):586–593. doi: 10.1289/ehp.1409645

Table 3.

Proportion of chemicals classified as active and concordance between assays among groups of Phase I chemicals.

Chemical class^a (number of chemicals)	Proportion active^b			Concordance^c
Chemical class^a (number of chemicals)	C. elegans	Zebrafish^P	Zebrafish^T	C. elegans and Zebrafish^P	C. elegans and Zebrafish^T	Zebrafish^P and Zebrafish^T
Amide (24)	0.58	0.75	0.75	0.75	0.50	0.75
Anilide (14)	0.64	0.79	0.86	0.86	0.50	0.64
Carbamate (15)	0.53	0.80	0.67	0.60	0.73	0.73
Conazole (18)	1.00	1.00	0.89	1.00	0.89	0.89
Organophosphate (35)	0.80	0.86	0.57	0.83	0.49	0.54
Phenoxy (12)	0.67	0.92	0.33	0.75	0.33	0.42
Pyrethroid (12)	0.92	1.00	0.67	0.92	0.58	0.67
Pyridine (10)	0.70	0.60	0.40	0.90	0.50	0.60
Urea (8)	0.63	0.75	0.63	0.38	0.50	0.38
^aChemical classes were derived from Judson et al. (2010). ^bChemical activity is based on the specific assays for Zebrafish^P (Padilla et al. 2012), Zebrafish^T (Truong et al. 2014), and C. elegans (this publication). ^cConcordance is defined as the proportion of chemicals with the same classification.