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. 2016 Apr;6(2):184–198. doi: 10.21037/qims.2016.04.01

Table 1. A summary of the key terms used to describe the pathological processes in osteomyelitis and their MRI signal characteristics.

Key term Pathological process MRI signal
T1 T2 T1 + C
Bone marrow oedema Accumulation of pus within the medullary cavity, leading to vascular congestion Low High High
Intraosseous abscess Formation of reactive bone and granulation tissue around intramedullary pus Low High Peripheral enhancement
Subperiosteal abscess Accumulation of pus beneath elevated periosteum Low High Peripheral enhancement
Cloaca A cortical defect that allows pus to drain between bone and soft tissue Low High Low
Sinus tract A channel, lined with granulation tissue, that allows pus to drain between bone and the skin surface Low High Peripheral enhancement
Sequestrum A separated fragment of necrotic bone that is surrounded by pus, granulation tissue and an involucrum Low Low Peripheral enhancement

MRI, magnetic resonance imaging.