The volume increase and the expanded margin. The total increase of PTV was calculated by (V_PTV_x − V_PTV_0)/ V_PTV_0 ×100%, and the volume increase per millimeter was calculated by (V_PTV_x − V_PTV_x-1)/V_PTV_x-1 (x=1, 2, 3, 4, 5). PTV, planning target volume; V_PTV_0, the volume of CTV_Lr in pCT; CTV, clinical target volume; pCT, planning CT; CTV_Lr, low-risk CTV region.