Table 2. The shape presentation parameters of all TVs in concurrent and sequential chemoradiotherapy subgroup (mean ± SD, 95% CI).
| Parameters | GTV_T |
GTV_Nl |
GTV_Ns |
CTV_Lr |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Seq | Con | P value | Seq | Con | P value | Seq | Con | P value | Seq | Con | P value | ||||
| OI_pCT | 0.62±0.18 (0.58, 0.67) | 0.56±0.19 (0.50, 0.62) | 0.074 | 0.75±0.18 (0.64, 0.86) | 0.38±0.22 (0.31, 0.46) | 0.000 | 0.53±0.15 (0.47, 0.59) | 0.36±0.20 (0.33, 0.40) | 0.000 | 0.92±0.04 (0.91, 0.93) | 0.89±0.05 (0.887, 0.90) | 0.000 | |||
| OI_rCT | 0.98±0.02 (0.97, 0.98) | 0.96±0.04 (0.95, 0.97) | 0.019 | 0.98±0.01 (0.98, 0.98) | 0.92±0.07 (0.90, 0.95) | 0.004 | 0.89±0.07 (0.86, 0.92) | 0.78±0.21 (0.74, 0.82) | 0.010 | 0.95±0.03 (0.94, 0.95) | 0.94±0.03 (0.94, 0.95) | 0.360 | |||
| DSC | 0.74±0.15 (0.71, 0.77) | 0.69±0.16 (0.64,0.74) | 0.091 | 0.84±0.13 (0.76, 0.92) | 0.51±0.21 (0.44, 0.58) | 0.000 | 0.66±0.13 (0.61, 0.72) | 0.47±0.21 (0.44, 0.51) | 0.000 | 0.93±0.03 (0.92, 0.94) | 0.91±0.03 (0.80, 0.92) | 0.002 | |||
| Mean SPD (mm) | 3.4±2.1 (3.0, 3.9) | 4.2±2.7 (3.4, 5.1) | 0.074 | 2.6±1.6 (1.5, 3.6) | 5.3±2.6 (4.5, 6.2) | 0.001 | 2.5±0.7 (2.2, 2.8) | 3.7±2.2 (3.3, 4.1) | 0.007 | 1.2±0.5 (1.0, 1.3) | 1.6±0.6 (1.4, 1.7) | 0.001 | |||
| Overall SD (mm) | 3.5±1.7 (3.1, 3.9) | 4.3±2.4 (3.6, 5.1) | 0.027 | 2.8±1.3 (2.0, 3.7) | 3.5±1.3 (3.0, 3.9) | 0.157 | 2.3±0.5 (2.1, 2.5) | 2.8±1.6 (2.5, 3.1) | 0.086 | 2.1±0.7 (1.9, 2.3) | 2.7±0.8 (2.5, 2.9) | 0.000 | |||
TV, target volume; SD, standard deviation; 95% CI, 95% confidence interval; Seq, sequential chemoradiotherapy; Con, concurrent chemoradiotherapy; GTV_T, GTV of the primary tumor; GTV_Nl, GTV of a large lymph node; GTV_Ns, GTV of a small lymph node (>1 and ≤3 cm); CTV_Lr, CTV of a low risk region; CRT, chemoradiotherapy; SPD, the shortest perpendicular distance; OI, overlapping index; DSC, dice similarity coefficient; GTV, gross tumor volume; CTV, clinical target volume.