Table 1.
Characteristics of children at time of initial ESRD onset in the entire cohort and by height category
| Characteristics at ESRD Onseta | Overall (n=13,218) | Short Stature (n=3418) | Normal Stature (n=9430; Reference) | Tall Stature (n=370) | P Value |
|---|---|---|---|---|---|
| Median age, years (IQR) | 14.5 (10.5–17.5) | 12.5 (7.5–15.5) | 15.5 (11.5–17.5) | 14.5 (10.5–17.5) | <0.001 |
| Age category, % (n) | <0.001 | ||||
| 2–5 years | 7 (916) | 12 (425) | 5 (471) | 5 (20) | |
| >5 to <13 years | 29 (3860) | 40 (1350) | 25 (2391) | 32 (119) | |
| ≥13 years | 64 (8442) | 48 (1643) | 70 (6568) | 62 (231) | |
| Race, % (n) | <0.001 | ||||
| White | 67 (8877) | 71 (2436) | 66 (6255) | 50 (186) | |
| Black | 24 (3142) | 18 (602) | 25 (2372) | 45 (168) | |
| Asian | 6 (773) | 7 (250) | 5 (515) | 2 (8) | |
| Native American | 2 (208) | 1 (48) | 2 (155) | 1 (5) | |
| Other | 2 (218) | 2 (82) | 1 (133) | 1 (3) | |
| Male, % (n) | 55 (7224) | 56 (1904) | 54 (5119) | 54 (201) | 0.36 |
| Cause of ESRD, % (n) | <0.001 | ||||
| Congenital/cystic/hereditary diseases/pyelonephritis/interstitial nephritis | 39 (5121) | 55 (1867) | 34 (3188) | 18 (66) | |
| GN (primary and secondary) | 25 (3294) | 13 (447) | 29 (2723) | 34 (124) | |
| FSGS | 15 (1969) | 11 (377) | 16 (1517) | 20 (75) | |
| Hypertension | 4 (555) | 3 (105) | 4 (421) | 8 (29) | |
| Other | 17 (2279) | 18 (622) | 17 (1581) | 21 (76) | |
| eGFR (ml/min per 1.73 m2) at ESRD onset,b median (IQR) | 7.6 (5.6–10.2) | 7.4 (5.6–9.9) | 7.7 (5.6–10.3) | 8.2 (5.7–11.0) | 0.02 |
| Medicaid, % (n) | 46 (6047) | 54 (1831) | 43 (4074) | 38 (142) | <0.001 |
| Average median neighborhood income ($) | 52,362 | 52,553 | 52,299 | 52,192 | 0.58 |
| Body mass index,c % (n) | <0.001 | ||||
| <5th percentile | 10 (1357) | 13 (428) | 9 (868) | 18 (61) | |
| 5th to 94th percentile | 72 (9370) | 70 (2356) | 73 (6809) | 59 (205) | |
| ≥95th percentile | 17 (2256) | 17 (579) | 17 (1597) | 23 (80) | |
| Death rate per 100 person-years (95% CI) | 1.74 (1.66 to 1.83) | 2.04 (1.88 to 2.23) | 1.61 (1.52 to 1.70) | 2.40 (1.89 to 3.05) |
IQR, interquartile range; 95% CI, 95% confidence interval.
a
All ESRD characteristics are broken down by height category (column percentages).
b
Missing in n=2308 owing to missing serum creatinine values, especially in patients with pre-emptive transplantation.
c
Missing in n=235.