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. 2016 May 6;6:114. doi: 10.3389/fonc.2016.00114

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Copyright © 2016 Mercado, Kress, Cyr, Chen, Yung, Bullock, Lei, Collins, Satinsky, Harter, Suy, Dritschilo, Lynch and Collins.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Average EPIC domain scores at baseline and following IMRT plus SBRT boost for prostate cancer. Shown are plots for: (A) EPIC urinary irritation/obstruction domain, (B) EPIC urinary incontinence domain, and (C) EPIC bowel domain. The thresholds for clinically significant changes in scores (½ SD above and below the baseline) are marked with dashed lines. IPSS scores range from 0 to 35 with higher values representing worsening urinary symptoms. EPIC scores range from 0 to 100 with higher values representing a more favorable health-related QOL. Thresholds for clinically significant changes in scores (½ SD above and below the baseline) are marked with dashed lines. EPIC scores range from 0 to 100 with higher values representing a more favorable health-related QOL.