Table 11.

Interaction effect of LEP CpG and SNP on FEV₁, FEV₁/FVC and FEF25-75% at 16 years of Age^* in BAMSE cohort

Parameter	Genotype	Estimate	Standard Error	p-value
FEV1
rs11763517	CT	0.01	0.05	0.83
	CT+TT	Ref.	Ref.
cg00666422		0.064	0.63	0.92
cg00666422*rs11763517	CT	0.37	1.26	0.77
	CC+TT	Ref.	Ref.
FEV1/FVC
rs11763517	CT	0.004	0.008	0.619
	CT+TT	Ref.	Ref.
cg00666422		0.019	0.097	0.84
cg00666422*rs11763517	CT	-0.18	0.19	0.347
	CC+TT	Ref.	Ref.
FEF25-75%
rs11763517	CT	0.047	0.11	0.679
	CT+TT	Ref.	Ref.
cg00666422		0.567	1.39	0.68
cg00666422*rs11763517	CT	-1.01	2.79	0.716
	CC+TT	Ref.	Ref.

^*Adjusted for maternal asthma, paternal asthma, maternal smoking, current smoking, height, and weight at age 16, and weighted for sex.