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(a,c) Represent the IL-6 concentration in vaginal tissue and plasma respectively. (b,d) Represent the TNF-α concentration in vaginal tissue and plasma respectively. Sol Cur, Sol EFV, CNP, ENP, Sol (Cur + EFV) and ECNPs were applied topically in vagina and IL-6 and TNF-α were estimated. Value of significance ***P < 0.0005, **P < 0.005, *P < 0.05.
