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. 2016 May 4;7:2041731416646676. doi: 10.1177/2041731416646676

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Cardiac function. A time course of changes in left ventricular ejection fraction (LVEF) following injection of cardiac cells into infarcted rat hearts. The baseline (immediately after surgery) values among treatment groups were not significantly different. At 1 week after treatment, although the LVEF of the control (CTL; PBS only) hearts decreased, the cell-injected hearts showed similar LVEF improvements. At 4 weeks after treatment, although the LVEF of cells in hydrogel (HG)-injected hearts increased, the LVEF of cells only (CO)-injected hearts decreased. Furthermore, only HG showed significant increase of LVEF between baseline and 4 weeks (+11.8% ± 8.0%, p < 0.01). In addition, the CTL hearts showed a further decrease in LVEF after 1 week (n = 8).