Figure 5.
sws-1 mutants are sensitive to genotoxins that induce HR repair substrates. Progeny survival of hermaphrodites treated with IR (A), MMS (B), HU (C), or CPT (D) as described in Materials and Methods. Survival was calculated as the number of adult progeny divided by the number of eggs and L1’s relative to untreated worms ± SEM from at least 22 adults over two trials. Statistical analysis was performed using Student’s t-test (*P < 0.01, **P < 0.0001).