Table 2.

Spontaneous resolution (polymorphisms combined)

	Univariate analysis		Synergy factor			Synergy index
Genotype	P‐value	OR (95% CI)	Synergy factor	P‐value	95% CI	Synergy index	95% CI
TapG:HLA‐B114D + IFN‐λ3/4 rs12979860 CC	<0.001	3.84 (2.10–7.03)	0.36	0.085	0.11–1.15	6.95	0.06–752.17
TapG:HLA‐B114D + KIR2DL3:HLA‐C1C1	0.012	2.37 (1.21–4.67)	2.83	0.194	0.59–13.56	0.97	0.41–2.32
IFN‐λ3/4 rs12979860 CC + KIR2DL3:HLA‐C1C1	0.070	1.98 (0.95–4.13)	3.32	0.067	0.92–11.95	0.59	0.20–1.70
IFN‐λ3/4 rs12979860 CC + HLA‐DRB1*04:01	0.004	5.10 (1.69–15.35)	1.92	0.473	0.32–11.44	0.95	0.17–5.30
TapG:HLA‐B114D + HLA‐DRB1*04:01	0.001	4.51 (1.79–11.36)	1.81	0.612	0.18–17.82	1.00	0.12–8.06
KIR2DL3:HLA‐C1C1 + HLA‐DRB1*04:01	0.999	6.2 × 109 (0‐.)	N/A	N/A	N/A	N/A	N/A
KIR2DS3 + KIR2DS5	0.240	0.48 (0.14–1.64)	0.29	0.1698	0.049–1.70	0.44	0.06–3.37

CI, confidence intervals; OR, odds ratio.