Table 3.
Sustained virological response to pegylated interferon/ribavirin (individual polymorphisms)
| Multivariate logistic regression | |||||
|---|---|---|---|---|---|
| Genotype | SVR n = 105 | No SVR n = 80 | P‐value | OR (95% CI) | |
| All genotypes | IFN‐λ3/4 rs12979860 CC | 42 | 23 | 0.265 | 1.50 (0.73–3.08) |
| KIR3DS1:HLA‐Bw4801 | 14 | 3 | 0.016 | 5.23 (1.35–20.19) | |
| KIR2DL2/S2:HLA‐C1C1 | 11 | 19 | 0.018 | 0.30 (0.11–0.82) | |
| KIR2DL2 | 45 | 47 | 0.742 | 0.88 (0.41–1.90) | |
| HCV G1 | IFN‐λ3/4 rs12979860 CC | 15 | 11 | 0.043 | 3.11 (1.04–9.32) |
| CA01CA01 | 17 | 15 | 0.098 | 2.51 (0.84–7.49) | |
| HCV G2/3 | KIR2DL3:HLA‐C1 | 50 | 15 | 0.018 | 4.90 (1.32–18.25) |
| CB01 | 9 | 9 | 0.137 | 0.38 (0.11–1.36) | |
CI, confidence intervals; OR, odds ratio; SVR, sustained virological response.