Table 6.
Genetic polymorphisms in disease progression
| Univariate analysis | Multivariate logistic regression | |||||
|---|---|---|---|---|---|---|
| Genotype | Cirrhosis n = 78 | No cirrhosis n = 208 | P‐value | OR (95% CI) | P‐value | OR (95% CI) |
| IFN‐λ3/4 rs12979860 CC | 36 | 74 | 0.174 | 0.69 (0.40–1.18) | 0.776 | 0.86 (0.30–2.48) |
| TapG:HLA‐B114D | 39 | 102 | 0.597 | 1.17 (0.66–2.07) | 0.637 | 1.29 (0.45–3.69) |
| KIR2DL3:HLA‐C1 | 45 | 131 | 0.393 | 1.34 (0.69–2.61) | 0.831 | 0.85 (0.19–3.77) |
| KIR2DL3:HLA‐C1C1 | 23 | 47 | 0.315 | 0.73 (0.40–1.34) | 0.399 | 0.63 (0.21–1.85) |
| KIR3DS1:HLA‐Bw4801 | 7 | 18 | 0.884 | 0.93 (0.37–2.34) | 0.336 | 0.44 (0.08–2.36) |
| KIR2DL2 | 32 | 114 | 0.071 | 1.65 (0.96–2.86) | 0.029 | 2.94 (1.12–7.73) |
| KIR2DS2:HLA‐C1C1 | 11 | 31 | 0.695 | 1.16 (0.55–2.46) | 0.772 | 0.76 (0.12–4.85) |
| KIR2DS3 | 15 | 54 | 0.106 | 1.71 (0.89–3.29) | 0.928 | 1.13 (0.88–14.45) |
| KIR2DS5 | 25 | 60 | 0.981 | 0.99 (0.56–1.77) | 0.332 | 1.72 (0.58–5.15) |
| CA01CA01 | 33 | 72 | 0.108 | 0.62 (0.34–1.11) | 0.792 | 1.48 (0.81–27.0) |
| CB01 | 10 | 53 | 0.034 | 2.25 (1.06–4.77) | 0.553 | 1.61 (0.33–7.76) |
| HLA‐DRB1*04:01 | 2 | 10 | 0.401 | 1.96 (0.41–9.47) | 0.182 | 4.39 (0.50–38.62) |
CI, confidence intervals; OR, odds ratio.