Table 2.
Body weight, heart weight, heart-to-body weight ratio, heart weight-to-tibia length ratio and left-ventricular wall thickness assessed by echocardiography
| ZL (n = 7–10) |
ZDF (n = 7–8) |
ZDF + Zn(ASA)2
(n = 5–6) |
ZL + Zn(ASA)2
(n = 8–10) |
|
|---|---|---|---|---|
| Weights | ||||
| Body weight (g) | 419 ± 9 | 376 ± 18 | 394 ± 27 | 416 ± 6 |
| Heart weight (g) | 1.36 ± 0.03 | 1.22 ± 0.04 | 1.35 ± 0.14 | 1.32 ± 0.03 |
| Heart-to-body weight (g/kg) | 3.26 ± 0.05 | 3.26 ± 0.11 | 3.39 ± 0.10 | 3.19 ± 0.07 |
| Heart weight-to-tibia length (g/cm) | 0.32± 0.01 | 0.30 ± 0.01 | 0.33 ± 0.03 | 0.30 ± 0.01 |
| Left-ventricular wall thickness | ||||
| LVPW, d (mm) | 2.49 ± 0.31 | 2.95 ± 0.42 | 1.95 ± 0.17 | 1.94 ± 0.20 |
| LVPW, s (mm) | 3.20 ± 0.27 | 4.24 ± 0.40 | 3.16 ± 0.19 | 2.69 ± 0.25 |
Values are mean ± SEM. ZL indicates Zucker lean, ZDF Zucker diabetic fatty acid, Zn(ASA) 2 zinc complex of acetylsalicylic acid, LVPW, d, thickness of the left ventricular posterior wall in diastole, LVPW, s thickness of the left ventricular posterior wall in systole, n number of animals analysed