Table 3.
Predicted mRNA targets of upregulated, differentially expressed microRNAs (orthologous and putative novel)
| Regenerating tissue source | Upregulated, differentially expressed microRNA | Predicted gene targets |
|---|---|---|
| regenerating tail tip | aca-miR-184 | adprhl2, anpep, ar, b3gnt1, bai2, ccar1, ccdc50, cdkn2c, cox4i2, depdc5, fam160a2, gpi, h6pd, kars, limk1, me1, ncan, nek6, oxnad1, pcsk4, pdia3, pdpk1, phlda1, ring1, rtn2, slc30a2, slc43a1, suclg1, sugp2, tgfb1, tmem214, usp21, xxylt1, G.11044, G.14682, G.15668, G.19327, G.19921, G.20484, G.21669, G.21917, G.21923, G.22240, G.22349, G.22365, G.22632 |
| regenerating tail tip | aca-miR-2188 | aaas, b3gnt7, crtac1, grm7, hsf1, hsp90b1, itpkb, itsn1, mta1, mylk2, nmnat3, pou2f2, tpd52, zbtb45, G.1698, G.6382 |
| regenerating tail base | 1_16347 (putative novel) | abcf3, adhfe1, amn1, c11orf35, cep76, chrna4, ddit4, dmtn, dpy30, dpysl3, fam57a, ikzf3, jarid2, lrrc4b, moxd1, mtpap, nmnat2, pfdn4, rps6kl1, scarf2, smpd2, sox13, sws2, tlk2, tpt1, tpx2, trmt1, G.11229, G.11992, G.14528, G.16037, G.19728, G.19926, G.4056 |
| regenerating tail base | 5_10675 (putative novel) | adam33, ap1b1, arhgef33, ccdc104, efcab4a, fermt2, ggt1, klhl38, ncoa4, nkd1, pipox, plxna4, ppfia4, psmc6, psmf1, rgs18, sall1, sdf2l1, traf3ip3, trim65, txlna, zfyve1, G.11978, G.20962, G.21441, G.4400 |
| regenerating tail base | aca-miR-1b | efhd1, irak4, sema4c, slain2, snai2, tktl1, G.22875, G.9382 |
| regenerating tail base | aca-miR-206 | ankrd17, c5orf30, cd44, cep192, chrac1, gbe1, notch3, poldip3, G.14293, G.4173, G.9382 |
| regenerating tail base | GL343237.1_6814 (putative novel) | ddb2, elmsan1, irf7, kank4, kifap3, klhdc3, ldb2, map1lc3b, nfia, orc4, ppp1r9b, ptprh, secisbp2, swap70, vash2, znf385c, G.12700, G.2381, G.3078, G.4859 |
| regenerating tail base | aca-miR-1a-1; aca-miR-1a-2 | ankrd17, efhd1, gbe1, ikbkap, irak4, pdgfa, sema4c, slain2, snai2, tktl1, G.14293, G.9382 |
| regenerating tail base | aca-miR-133a-1; aca-miR-133b | abcf3, adhfe1, amn1, arhgdia, c10orf12, c11orf35, cacna1b, cep76, cfdp1, chrna4, col1a1, creld1, ddit4, dmtn, dpy30, dpysl3, fam57a, gria1, gtpbp1, ikzf3, lrrc4b, moxd1, mtpap, nmnat2, pfdn4, ppapdc2, rps6kl1, scarf2, smpd2, sox13, tm2d3, tpt1, tpx2, trmt1, vcp, G.10949, G.11229, G.11992, G.14528, G.16037, G.19284, G.19728, G.19926, G.3656, G.4056, G.5104 |