Fig. 3.

D. vulgaris protein interaction network. All 459 interactions present in the high confidence interaction network are shown. Spoke model (bait-to-prey) interactions are indicated with solid arrows, and matrix model (prey-prey) interactions are shown with dashed lines. Gold-positive interactions inferred from 10-fold cross-validation are shown in purple color. All proteins are colored according to their assigned TIGR role as indicated. Gray areas enclose complexes discussed in the supplemental text associated with sulfate reduction and energy conservation (a₁–a₃), cofactor biosynthesis (b₁–b₃), RNA synthesis and degradation (c₁–c₃), motility (d₁–d₃), megaplasmid encoded complexes (e₁–e₅), and novel and uncharacterized complexes (f₁–f₂).