Fig. 5.

Hypothetical models. (A) The POI is recruited to the membrane proximity by MinC, MinD, or MinE (Min). It may subsequently interact with the inner membrane directly. (B) Exclusion of POI from the inner membrane by the Min proteins. (C) The aberrant division in the Δmin mutant shows a metabolic modulation phenotype that could be due to an imbalance between membrane-bound and cytosolic pools of the metabolic enzymes. Alternatively, uncharacterized stress responses could be involved in modulating the metabolic flux. Blue ovoid, nucleoid; orange circle, FtsZ ring.