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Hsp90 controls HIV transcription. Shown is the Dual-Glo luciferase assay at 37 and 39.5 °C and at 39.5 °C with 17-AAG in HIV-infected 8E5/LAV cells (left) and in uninfected Jurkat T cells (right). Data represent mean ± S.E. (error bars) (n = 4). *, p < 0.0001 by Student's t test comparing luciferase expression at 39.5 °C with luciferase expression at 39.5 °C in the presence of 1 μm 17-AAG.
