Skip to main content
. 2016 Mar 8;291(19):10332–10346. doi: 10.1074/jbc.M116.717538

FIGURE 6.

FIGURE 6.

Heat shock (39.5 °C) accelerates HIV transcription in persistently infected cells. A, virion RNA and p24 levels in culture supernatants from 8E5/LAV cells at 37 and 39.5 °C and in the presence of 100 μg/ml IUdR. p < 0.02 comparing 8E5/LAV RNA copy number at 37 °C with 8E5/LAV RNA copy number at 39.5 °C, 37 °C + IUdR, and 39.5 °C + IUdR by Student's t test. p < 0.0001 comparing 8E5/LAV p24 at 37 °C with 8E5/LAV p24 at 39.5 °C, 37 °C + IUdR, and 39.5 °C + IUdR by Student's t test. B, cell-associated HIV RNA and supernatant p24 levels from 8E5/LAV cells treated at 39.5 °C with cycloheximide (Chx). *, p < 0.0001, comparing 8E5/LAV p24 at 39.5 °C with 8E5/LAV p24 at 39.5 °C in the presence of cycloheximide. Data in both graphs represent mean ± S.E. (error bars) (n = 4).