Table 2.
Association of average pain intensity with demographic, clinical and behavioral factors in patients with DM1 and DM2.
| Feature | DM1 | Univariate analysis (p) | Multivariate analysis (beta, p) | DM2 | Univariate analysis (p) | Multivariate analysis (beta, p) |
|---|---|---|---|---|---|---|
| Demographic and clinical | ||||||
| Females % | 55.8 | 0.162 | n.i. | 68.2 | 0.016 | +0.38, 0.002 |
| Age at onset ** years, mean ± SD | 25.3 ± 8.6 | 0.337 | n.i. | 37.4 ± 12.0 | 0.882 | n.i. |
| Duration mean ± SD | 19.9 ± 9.7 | 0.001 | +0.47, 0.001 | 16.0 ± 13.4 | 0.017 | +0.08, 0.548 |
| Age ** years, mean ± SD | 45.0 ± 10.7 | 0.194 | n.i. | 53.4 ± 11.1 | 0.006 | +0.03, 0.847 |
| MRC score mean ± SD | 16.1 ± 2.6 | 0.017 | -0.17, 0.389 | 17.0 ± 2.3 | 0.002 | -0.12, 0.409 |
| INQoL weakness mean ± SD | 48.9 ± 36.8 | 0.049 | +0.20, 0.129 | 60.6 ± 32.5 | 0.000 | +0.58, 0.000 |
| INQoL locking mean ± SD | 44.1 ± 37.9 | 0.107 | n.i. | 42.3 ± 34.4 | 0.013 | +0.18, 0.199 |
| Active myotonia ** s, mean ± SD | 5.9 ± 2.4 | 0.697 | n.i. | 1.8 ± 1.9 | 0.686 | n.i. |
| Percussion myotonia ** s, mean ± SD | 8.8 ± 2.4 | 0.282 | n.i. | 3.7 ± 7.9 | 0.408 | n.i. |
| R2 adjusted | 0.20 | 0.44 | ||||
| Behavioral | ||||||
| HamD score ** mean ± SD | 13.3 ± 8.0 | 0.022 | -0.01, 0.943 | 7.8 ± 8.0 | 0.001 | +0.17, 0.211 |
| INQoL emotions mean ± SD | 29.2 ± 30.2 | 0.057 | n.i. | 32.3 ± 25.2 | 0.000 | +0.62, 0.000 |
| DSS mean ± SD | 5.8 ± 2.9 | 0.076 | n.i. | 5.1 ± 2.8 | 0.462 | n.i. |
| FSS mean ± SD | 35.2 ± 13.0 | 0.003 | +0.41, 0.003 | 38.2 ± 15.5 | 0.000 | +0.32, 0.064 |
| INQoL fatigue mean ± SD | 41.9 ± 39.1 | 0.020 | +0.18, 0.221 | 54.3 ± 33.8 | 0.000 | +0.19, 0.305 |
| R2 adjusted | 0.15 | 0.37 |
**
p<0.01 when compared patients with DM1 and DM2; n.s. non-significant; n.i. not included in the multivariate analysis since it was non-significant in univariate analysis