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. 2016 May 6;36(3):e00328. doi: 10.1042/BSR20160048

Figure 4. Knockdown LncRNA DQ786243 inhibited cell migration and invasion in vitro.

Figure 4

(A) Cell migratory abilities were measured by a wound healing assay. The wound areas were measured by ImageJ software. These data are shown as the mean±S.D. of three independent experiments. (B) Transwell invasion (crystal violet staining, original magnification ×200). SW620 and HT29 cells transfected with si-DQ786243 had a little cells migrated through the basement membrane, compared with si-Scramble and Blank groups (**P<0.01). No significant difference was observed between si-Scramble group and Blank group (P > 0.05). (C) The expression of EMT-related proteins in SW620 and HT29 cells by western blot. The levels of ZEB1 and E-cadherin were down-regulated in SW620 and HT29 cells transfected with si-DQ786243 (*P<0.05, **P < 0.01). But, the expression of Vimentin and N-cadherin were significantly increased in the both cells (**P<0.01).