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Senescence induction by radiation ± WIN2. MCF-7 cells were treated with vehicle, WIN2 (12 μM), (2 Gy) radiation or WIN2 + radiation. (A) Representative images of β-galactosidase stained cells. (B) Quantification of β-galactosidase activity 96 hours after drug treatment. Data were normalized to percentage of sample in (B); data presented reflect the means of three individual experiments ± S.E.; *P < 0.05 versus vehicle.
